Monday, August 16, 2021

"Why does he mean more to you than us?”

I come from the buckle of the Bible belt and I stay in touch with friends from back home. Nothing here is that new to me, but even if you've heard this story before, this retelling is worth your time. 

What I want to single out here is the way that MAGA and other movements can use members' deeply held (and often reasonable) beliefs to bring them in and then, once they are completely immersed, indoctrinate them into a new worldview that often directly contradicts some of those initial beliefs. This is not a simple process. It happen slowly and stealthily and its effectiveness is not limited to the stupid or the gullible. I've seen smart, reasonable people -- the last ones you'd expect -- get sucked in.  

Of course, more often it is the first ones you'd expect, cruel and foolish people with longstanding reactionary tendencies. The closer to the door they start, the easier it is to get them in the temple, but even the most likely recruits are changed by the indoctrination, made less empathetic, more childish, more paranoid and yet more credulous.   

From the Washington Post:

Like other families with split political affiliations, they had some yelling matches after Trump took office, especially over the former president’s immigration policies. Claire was a Canadian-born Catholic drawn to the Republican Party by her fierce opposition to abortion, and Trump had won her over with promises to champion her position. Celina, Laurie and their three younger siblings skewed left despite their conservative upbringing in South Dakota. They had never felt such disdain for a politician before.

By the end of the Trump administration, the bounds of their political disagreements had shifted, Laurie recounted, becoming at once more intense and also less about policy and legislation in Washington. They had learned to live with their disagreements over abortion. Now it felt like they were occupying different realities altogether.

Over the course of 2020, amid a presidential election, racial justice protests and a pandemic, the five siblings began to trade increasingly worried text messages and emails about some of the things Claire was saying and posting on Facebook. There were comments they noticed about child trafficking and sacrifice, a key theme of the extremist QAnon ideology. There was her vitriol toward Pope Francis, whom she had referred to as “the anti-Pope.” After Election Day, they took turns pushing back on a stream of disinformation Claire posted online, including the unfounded claim that the CIA murdered U.S. soldiers abroad to help cover up voter fraud.

...

“Why is this important enough to compromise your relationships with your kids? Why does he mean more to you than us?”
This is a topic that could launch a thousand graduate theses, so we need to come back to it, particularly what happens to an area when conservative media reaches critical mass (we will cover this). In the mean time, one closing thought: cults and cons exist because people believe they would never fall for a cult or a con.

Friday, August 13, 2021

Ten years ago at the blog -- Conservation of Cynicism

 

It's all really the same thread. Back in 2011, we were talking about the consequences of the conservative movement cultivating craziness and manipulating the base through disinformation. We just have more examples now. 


SUNDAY, JULY 31, 2011

Overly-trusting Straussians

There is a strong strain of Straussianism in the conservative movement. Of course, not all prominent conservative intellectuals believe that you have to lie and oversimplify to move the masses in the best direction for society, but pretty much all have accepted and, more importantly, internalized the fact that many of their colleagues do believe in the need for these noble lies.

Once you've internalized the idea that people in your circle are smart and sane but occasionally make ludicrous statements for the benefit of the crowds (call it the Elsinore strategy -- feigning madness), it becomes easy to ignore craziness in your own party, particularly when there's a penalty for suggesting the alternative (see Bartlett and Frum).

In other words, we have something like conservation of cynicism. The Straussian assumes the worst about the masses, but has an excuse to assume the best about allies, even when they give every indication of being crazy and/or stupid. The result is that it has taken smart, sane conservatives far too long to acknowledge what's going on with House Republicans.

The consequences of this lack of cynicism is spelled out in detail in excellent posts by Jon Chait and Paul Krugman.

Thursday, August 12, 2021

To quote Robin Williams, "Does the name Custer mean anything to you?" -- more on feral disinformation and sane vampires

We've already done a couple of posts (here and here) on this, but a recent post at TPM got me to thinking that I hadn't emphasized enough how difficult this situation is for the Republicans.

Here's the relevant section from our original post.

Disinformation has gone feral when:

1. It is no longer in the control of the group that created it.

2. It has continued to grow in popularity and influence.

3. It has started to evolve in such a way that the nuisance/threat it presents is as as great to the people who created it as it does to the original targets. 

The most prominent example of the moment is the right wing movement opposing covid vaccines and increasingly vaccination in general. 

The Conservative Movement spent decades depicting the scientific establishment as alarmist and corrupt because undermining it served a clear political purpose at the time. Recently this narrative took on an added usefulness as the Republicans tried to contain the fallout from the pandemic. It was an unspeakably evil position to take, greatly adding to a horrific death toll, but it had a certain ends-justify-the-means logic, "had" being the operative word.

In 2021, being the anti-vaxx party is not in the Republicans' best interest. It devastates  areas that voted for Trump and it makes the most comically crazy people imaginable the face of the GOP. On top of that, it's bad for business. 

The best messaging for the Republicans at this point would be to start referring to the "Trump vaccines" and to work the phrase "Operation Warp Speed" into every statement and interview response, regardless of topic, then take credit for the end of the pandemic. That is, however, not an option. Control of the narrative has been lost, Things have gone feral.

Though the Conservative Movement reaped considerable benefits for decades by cultivating paranoia and conspiracy-thinking, the Republicans are now far past the cunning scheme phase on this. 

Here's Josh Marshall:  

Among Americans over the age of 18 fully 71% have gotten at least one vaccine dose.

As an epidemiological matter we need all that 71% to get both their shots. Currently that fully vaccinated number is 61%. And that should shift significantly over the next few weeks as many of those people get their second shots and then wait for two more weeks for the full immune effect to take hold. But as a proxy for being for or against vaccines, even the single shot is a good measure. And that means that an overwhelming majority of the people who participate meaningfully in the national political conversation and have even the right to vote are vaccinated.

This becomes even more the case when you add in the age factor. Voter participation almost universally goes up with age. The same is true with COVID vaccines. 90% of Americans over 65 have had at least one shot. And in basically every age segment from age 12 on up the vaccination rate gets higher. Point being, among the voting public the vaccinated already overwhelmingly outnumber the unvaccinated.

The Wall Street Journal published an article yesterday about how vaccination status is increasingly dividing Americans. “From family gatherings to weddings to workplaces, vaccinated Americans are drawing new, sharper lines around who they choose to spend time with amid the rise of the highly-transmissible Delta variant. And the unvaccinated are growing testy over being excluded and feeling judged for exercising their right to make their own health choices.”

At the risk of over simplifying, we have about two thirds of the country more and more annoyed and even angry at around one quarter who in turn are burrowing even deeper into their long-standing persecution complexes, with the imbalance almost certain to grow and the emotions to intensify. The sane vampires of the GOP face an insurmountable challenge on vaccines. They know how unpopular the con position is but they also know that, as a small tent party, they can't afford to alienate the lunatic fringe they cultivated. 

Interestingly, one result has been, contrary to stereotype, conservative outlets like the WSJ suggesting we should be more sensitive to the feelings of the unvaccinated while the position on the left is increasingly "stop being a baby and get your goddamn shot." I'm absolutely convinced the sane vampires would like to say this too, but their window for being honest with the base has long since closed. 

Wednesday, August 11, 2021

America has a children of famous parents problem

I've been meaning to repost this for a few weeks now, ever since I saw a Twitter exchange between Ben Dreyfuss and Josh Barro whining about train travel (Barro also had a let them eat cake comment about public libraries, but I'm not sure it was part of the same thread). I was familiar with Barro, an unimpressive writer whose rapid success would be pretty much unimaginable for someone without big time family connections. ("[Robert] Barro is considered one of the founders of new classical macroeconomics, along with Robert Lucas, Jr. and Thomas J. Sargent.") Dreyfuss, though, has him beat. First his father Richard Dreyfuss set him up as an actor, then when that didn't work out, his sister got him a job as a professional tweeter.

Just to keep things in perspective, these two are, at worst annoying. The Cuomo brothers are despicable and in terms of damage done, G.W. Bush is in a category of his own. These men didn't just get a leg up; they have traveled their entire lives on greased skids. There are far too many other examples. We have a nepotism problem.

I don't want to paint with too broad a brush. While people like Michael Douglas and Jane Fonda, Randy and Thomas Newman,  Chris Wallace and Maggie Haberman certainly had an advantage starting out, their subsequent work suggests that, with a little luck, they might have had roughly the same careers without the same parents. 

Obviously, in a perfect world, we'd all have an equal shot, but as long as connections are merely helpful, we can live with the unfairness. When being born in the right place and knowing the right people becomes a sufficient condition for success, we're in trouble. 


From back in 2014, we had an exchange with Gelman on the topic. 

MONDAY, JANUARY 20, 2014

Are we becoming more tolerant of nepotism (and other perks of privilege)?

The New Republic has a very good profile by Julia Iofee of  Michael Needham of the Heritage Foundation. The whole thing is worth reading, but there's one paragraph I'd like to single out both because of its content and its placement deep in the article.
After [Michael] Needham graduated from Williams in 2004, Bill Simon Jr., a former California Republican gubernatorial candidate and fellow Williams alum, helped Needham secure the introductions that got him a job at the foundation. Ambitious and hard-working, he was promoted, in six months, to be Feulner’s chief of staff. According to a former veteran Heritage staffer, Needham is intelligent but “very aggressive”: “He is the bull in the china closet, and he feels very comfortable doing that.” (“I consider him a friend,” says the college classmate, “but he’s a huge asshole.”) In 2007, Needham, whose father has given generous donations to both Rudy Giuliani and the Heritage Foundation, went to work for Giuliani’s presidential campaign. When the campaign folded, Needham followed his father’s footsteps to Stanford Business School and then came back, at Feulner’s bequest, to run Heritage Action.
You'll notice Iofee goes out of her way to suggest that Needham got his first rapid promotion by being "ambitious and hard-working," and there is, no doubt, some truth in that, but pretty much everybody who goes to work for a big-time D.C. think tank is ambitious and hard-working. These are not traits that would have set Needham apart while being the socially well-connected son of a major donor very well might have.

My question is: would this angle have been handled differently a few years ago? Obviously nepotism and advancement through connection have always been with us, but until recently I get the impression that this career path was seen as somewhat suspect; people who obviously got their positions thanks to string-pulling were put on a kind of public probation until they had proven themselves.

Now, the public (or at least the press) seems to me much less likely to discount the accomplishments of the well-connected children of the rich and powerful. Along similar lines, though you can certainly still find jokes about the boss's son/nephew/brother-in-law, but they don't seem nearly as pervasive as they were through most of the 20th Century. Anyone else see a trend here?

Tuesday, August 10, 2021

They literally call these "pump and dumps"

No, really. They actually use those words. The victims know exactly what's going to happen but never imagine it will happen to them. Never has Maurer's The Big Con seemed so relevant.

Monday, August 9, 2021

Autogyros were cool

And we haven't done a flying machine post for ages.

The technology was still cutting when this film was shot in 1931.






You Only Live Twice was perhaps the stupidest of the series, with the "let Bond go so we can kill him later" tactic reaching possibly a franchise peak. It is also, if you catch it in the right mood, a lot of fun, with piranha tanks, ninjas, and perhaps the most over-the-top Ken Adam set design.

Like the rocket belt in Thunderball, the Wallis WA-116 Agile in YOLT was the real thing, flown by its inventor, Ken Wallis. The armaments are goofy and the doubling leaves something to be desired, but how often do you get to see aerial combat with a genuine autogyro?   









Friday, August 6, 2021

For some reason completely unrelated to the rest of the post, this classic science fiction story came to mind

"The Marching Morons" by Cyril M. Kornbluth is a 1951 story about a con man who suckers gullible people into a doomed flight to another planet.

_____________________________________________________________

For the weekend, three videos from the Common Sense Skeptic.


I assume everyone still remembers Mars One, the widely reported plan to use a reality show to finance a permanent Martian colony. The Gateway SpacePort is also a plan for establishing a privately funded foothold in space, but it's not as reputable or well thought-out.








The 2001 tweet was one of those reminders that Elon Musk doesn't have a grasp of even the basics of manned space travel. We discussed some of the issues here but this video (also by the Common Sense Skeptic) explains the problems better and in much greater detail.




Even if the orbital hotels and the artificial gravity don't work out, space travel can still be luxurious.
Elon Musk, whose firm SpaceX is building a rocket that could transport up to 100 people in space at once, has a vision for future space activities. On Wednesday, the CEO shared an image with his 31 million Twitter followers envisioning a musical performance in a ship above the Earth.

"Starship Concerto in Zero G," Musk wrote alongside the image, referring to the name of the stainless steel rocket currently in the prototype phase. It wouldn't be the first musical performance in space – Chris Hadfield famously covered David Bowie's "Space Oddity" on board the International Space Station – but the Starship could represent an opportunity for more artists than ever to be inspired by the amidst the stars.
...

Those passengers would have plenty of room to stretch out and get creative. The Starship is expected to offer 100 cubic meters of pressurized cabin space, similar to an Airbus A380 or the International Space Station. Musk noted at a September 2019 event that, thanks to zero gravity, space could be used much more efficiently as users would be able to take advantage of every corner of a room.





Thursday, August 5, 2021

Europe envy

This is Joseph

One thing that I always find intriguing is how much people seem to point to European countries as examples of better places to live as compared to North America. The envy of Scandinavia is long standing and people from the UK are seen as being classy but recently there seems to a new target: Hungary


As a person who has traveled to Europe a fair bit, I always find this attitude a bit odd. Now, this is not to say that I do not have interest in stealing good ideas from other places (wearing masks for people with active respiratory illness as a matter of social politeness is an idea I would love to steal from Japan). 

That said, there are always two points to keep in mind.

One, it depends a lot on who you are as to whether a specific system is better for you. If you are an immigrant you are better off seeking to live in Canada than Hungary, at least on average, in terms of acceptance. If you have no money and health issues, then maybe you want to live in a place like Canada or the UK which have decent free health care. But if you are sick and have money then I want to be in France -- even libertarians agree

Two, is that it depends a lot on social class. People who have the resources to visit Europe and who are able to move around the globe are likely upper middle class. I think it is obvious that the best place to be upper middle class, assuming you stay upper middle class, is probably the United States. Even the arguments about the poor climate seem to presume that people have yet to visit California.  

That said, I take Matt's point that which European country that people envy is a great way to get a sense of what is or is not valued. Not a universal point, preferences can be eccentric. But I always figured that the UK class system is what people in Canada envied -- liking the idea of social hierarchy that is a lot less present in Canada, despite the overall great standard of living in Canada. I would find envy of Russia concerning unless it was envy of something that was a very specific value (e.g., winter sports or cuisine). 

In any case, it has been fun to watch the defenses of Hungary, There are some really nice features about Hungary but I am still pretty convinced the best place in the world to be middle class is still the United States. Certainly, the pattern of immigration suggests the same. 

Wednesday, August 4, 2021

The good news is I can run it again since nothing has changed. The bad news is I can run it again since nothing has changed -- Mega-fire repost 3

 TUESDAY, SEPTEMBER 22, 2020

West Coast wildfires -- Marketplace gets it right

At first glance, this shouldn't be that difficult. You just have to hit the following points clearly and emphatically.

1. While climate change contributes to the wildfire crisis, the much larger and more immediate cause is the result of decades of excessive Western fire suppression.

2. We desperately need to address this crisis as soon as possible, primarily through controlled and managed burns.

3. The scientists studying forests are in absolute agreement on both these points and have been warning us about this crisis for years.

4. However, a combination of governmental inaction, perverse incentives and the short-sighted self-interest of various parties has kept us from avoiding catastrophe.

Not one in ten articles on the subject meets these standards, but perhaps we shouldn't be that surprised. Telling a story that grows out of the facts, fighting the urge to bend it to fit popular narratives, keeping the focus on the genuinely important. These are things that require journalists to have both skill and courage.

Which is part of the reason why Marketplace is the best daily news show on public radio.


Tuesday, August 3, 2021

The good news is I can run it again since nothing has changed. The bad news is I can run it again since nothing has changed -- Mega-fire repost 2

 

TUESDAY, SEPTEMBER 8, 2020

"California would need to burn 20 million acres — an area about the size of Maine — to restabilize in terms of fire"

The sky here in LA has taken on that distinct orange tint. Just as the heat has started to let off, the air is turning bad. Another large fire has broken out in the Angeles Forest. [Emphasis added]

The rugged terrain, access and triple-digit temperatures created difficult and dangerous conditions for firefighters. During a Monday afternoon press conference, officials expressed concern that winds in the coming days would change the direction of the flames, pushing them down the mountains toward foothill communities in the San Gabriel Valley.

If that happens, authorities said the communities that would impacted first would be Monrovia and Duarte. Residents in those areas are being urged to be prepared to evacuate. Bradbury, Azusa, Arcadia and Sierra Madre could also potentially see either evacuation warnings or orders.

"Directly coming into Monrovia or Duarte, no, that area has not burned in 50 to 100 years in some places, so the fuel-loading is high and there is not a natural break from the fuels from previous fires," said incident commander Steve Goldman.
As Elizabeth Weil explains in her Pulitzer-worthy Propublica piece (which we discussed earlier here), this is not just a dangerous but an unnatural situation. [again, emphasis added]
Yes, there’s been talk across the U.S. Forest Service and California state agencies about doing more prescribed burns and managed burns. The point of that “good fire” would be to create a black-and-green checkerboard across the state. The black burned parcels would then provide a series of dampers and dead ends to keep the fire intensity lower when flames spark in hot, dry conditions, as they did this past week. But we’ve had far too little “good fire,” as the Cassandras call it. Too little purposeful, healthy fire. Too few acres intentionally burned or corralled by certified “burn bosses” (yes, that’s the official term in the California Resources Code) to keep communities safe in weeks like this.

Academics believe that between 4.4 million and 11.8 million acres burned each year in prehistoric California. Between 1982 and 1998, California’s agency land managers burned, on average, about 30,000 acres a year. Between 1999 and 2017, that number dropped to an annual 13,000 acres. The state passed a few new laws in 2018 designed to facilitate more intentional burning. But few are optimistic this, alone, will lead to significant change. We live with a deathly backlog. In February 2020, Nature Sustainability published this terrifying conclusion: California would need to burn 20 million acres — an area about the size of Maine — to restabilize in terms of fire.

...

[Deputy fire chief of Yosemite National Park Mike] Beasley earned what he called his “red card,” or wildland firefighter qualification, in 1984. To him, California, today, resembles a rookie pyro Armageddon, its scorched battlefields studded with soldiers wielding fancy tools, executing foolhardy strategy. “Put the wet stuff on the red stuff,” Beasley summed up his assessment of the plan of attack by Cal Fire, the state’s behemoth “emergency response and resource protection” agency. Instead, Beasley believes, fire professionals should be considering ecology and picking their fights: letting fires that pose little risk burn through the stockpiles of fuels. Yet that’s not the mission. “They put fires out, full stop, end of story,” Beasley said of Cal Fire. “They like to keep it clean that way.”

Monday, August 2, 2021

The good news is I can run it again since nothing has changed. The bad news is I can run it again since nothing has changed -- Mega-fire repost 1

THURSDAY, SEPTEMBER 3, 2020

The truth about Western megafires is the narrative no one wants to hear.

Every few years, some journalist will do a solid, deeply reported story on Western megafires. (This Propublica piece by Elizabeth Weil is excellent. I also recall a good series from NPR a while back.) These articles always say basically the same thing about the scientific consensus, the severity of the problem and the steps we need to take. They are always persuasive, always told with a great sense of urgency, and always ignored. This is what happens, at least these days, when a crisis and its solutions break with conventional narratives and  require great political will to address.

The doomed California genre plays both to very real environmental concerns and to a longstanding Eastern schadenfreude, the epicenter of which is located in the editorial offices of the New York Times. The Golden State is supposedly burning for its environmental sins but in reality this is not primarily a climate change story. While increased heat and more severe droughts exacerbate the situation, we would still be having megafires without them.
A seventy-word primer: We dug ourselves into a deep, dangerous fuel imbalance due to one simple fact. We live in a Mediterranean climate that’s designed to burn, and we’ve prevented it from burning anywhere close to enough for well over a hundred years. Now climate change has made it hotter and drier than ever before, and the fire we’ve been forestalling is going to happen, fast, whether we plan for it or not.

Megafires, like the ones that have ripped this week through 1 million acres (so far), will continue to erupt until we’ve flared off our stockpiled fuels. No way around that.
Fires are an essential part of the life cycle of these forests. Controlled burns return the forests to a more normal equilibrium. If we listened to the scientific consensus, they would be the main weapon in our arsenal. Unfortunately science is not the main consideration here.

By comparison, planning a prescribed burn is cumbersome. A wildfire is categorized as an emergency, meaning firefighters pull down hazard pay and can drive a bulldozer into a protected wilderness area where regulations typically prohibit mountain bikes. Planned burns are human-made events and as such need to follow all environmental compliance rules. That includes the Clean Air Act, which limits the emission of PM 2.5, or fine particulate matter, from human-caused events. In California, those rules are enforced by CARB, the state’s mighty air resources board, and its local affiliates. “I’ve talked to many prescribed fire managers, particularly in the Sierra Nevada over the years, who’ve told me, ‘Yeah, we’ve spent thousands and thousands of dollars to get all geared up to do a prescribed burn,’ and then they get shut down.” Maybe there’s too much smog that day from agricultural emissions in the Central Valley, or even too many locals complain that they don’t like smoke. Reforms after the epic 2017 and 2018 fire seasons led to some loosening of the CARB/prescribed fire rules, but we still have a long way to go.

“One thing to keep in mind is that air-quality impacts from prescribed burning are minuscule compared to what you’re experiencing right now,” said Matthew Hurteau, associate professor of biology at University of New Mexico and director of the Earth Systems Ecology Lab, which looks at how climate change will impact forest systems. With prescribed burns, people can plan ahead: get out of town, install a HEPA filter in their house, make a rational plan to live with smoke. Historical accounts of California summers describe months of smoky skies, but as a feature of the landscape, not a bug. Beasley and others argue we need to rethink our ideas of what a healthy California looks like. “We’re used to seeing a thick wall of even-aged trees,” he told me, “and those forests are just as much a relic of fire exclusion as our clear skies.”
 
In the Southeast which burns more than twice as many acres as California each year — fire is defined as a public good. Burn bosses in California can more easily be held liable than their peers in some other states if the wind comes up and their burn goes awry. At the same time, California burn bosses typically suffer no consequences for deciding not to light. No promotion will be missed, no red flags rise. “There’s always extra political risk to a fire going bad,” Beasley said. “So whenever anything comes up, people say, OK, that’s it. We’re gonna put all the fires out.” For over a month this spring, the U.S. Forest Service canceled all prescribed burns in California, and training for burn bosses, because of COVID-19.
In my more pessimistic moments, I think we are in a post-solution America, a country that talks a better and better game but has lost its taste for actually solving problems. Lately, those pessimistic moments have become more frequent.

Friday, July 30, 2021

Andy and the anti-vaxxer

It's useful to step back from time to time and remind ourselves just how far beyond precedent the Republican party has drifted. The following clip aired in March of 1962. It came from one of the most popular shows of the decade, especially in rural America. 

There was nothing controversial about assuming that vaccination was a public good or about depicting the vaccine-hesitant as backwards and uneducated. Audiences would have found it strange to think otherwise. As with many other issues, the Right's "reactionary" positions are not actually a move back to popular attitudes from the past. They are instead new and radical and would have been seen as crazy sixty years ago.


Thursday, July 29, 2021

The Greatest Post-Script in TED Talk History

I wish I'd known about this video before I wrote the post.



Scam artists locking in on citizen science was another one we should have seen coming.






THURSDAY, APRIL 1, 2021

The almost perfect 2021 business story: funded by the likes of Andreessen Horowitz, feted by goop, it was a massive fraud built around a literal shit company

If only they could have gotten Musk and Thiel involved.

 

SF poop-testing startup, once compared to Theranos, charged in $60M fraud scheme

Zachary Schulz Apte and Jessica Sunshine Richman, co-founders of defunct microbiome testing company uBiome, are accused of bilking their investors and health insurance providers, federal prosecutors said. They were indicted Thursday on multiple federal charges, including conspiracy to commit securities fraud, conspiracy to commit health care fraud and money laundering.

...

Apte, 36, and Richman, 46, founded uBiome in 2012 as a direct-to-consumer service called “Gut Explorer.” Customers would submit a fecal sample that the company analyzed in a laboratory, comparing the consumer's microbiome to others' microbiomes, prosecutors said. The service cost less than $100 initially.

The company grew to include “clinical” tests of gut and vaginal microbiomes, which were aimed to be used by medical providers so uBiome could seek up to $3,000 in reimbursements from health insurance companies. The federal indictment states that uBiome sought upwards of $300 million in reimbursement claims from private and public health insurers between 2015 and 2019. The company was ultimately paid more than $35 million for tests that “were not validated and not medically necessary."

Apte and Richman met in San Francisco in 2012 through the California Institute for Quantitative Biosciences Garage, an incubator used by UCSF. Together, they founded uBiome and received funding from Silicon Valley investors like 8VC in San Francisco and  Andreessen Horowitz in Menlo Park, which hold 22% and 10% stakes in uBiome, respectively, according to court documents.

For a time, they were the latest up-and-coming business determined to disrupt the medical testing industry. In 2018, Richman was even named an "innovator" winner in Goop's "The Greater goop Awards" and at its peak, uBiome was valued at $600 million.

Tuesday, July 27, 2021

Counterfactuals and age

This is Joseph.

I was reading Andrew Gelman's post on potential outcomes and it reminded me of the classic problem with this parameter in epidemiology, namely chronological age. I like potential outcomes for a lot of questions -- what happens if we change an exposure and create a counterfactual outcome is a very logical way to think about things like prescription drugs, milk in the diet, and water purity. There is a reasonable causal contrast between exposed and unexposed that could be estimated (e.g., it is true in expectation in a randomized controlled trial).

It gets trickier with other variables. Sex (as opposed to gender) is difficult to imagine being anything but a theoretical contrast (gender, on the other hand, is a lot more complicated). Similarly, disentangling the effects of race as a genetic piece (usually very small) versus racism is a very challenging causal inference problem. You can imagine changing the racist nature of society but not really genotypes. Smart people work on this problem, but I think of it as quite hard (and thus I am glad for the smart people).

But the biggest challenge is age. Age is a very important etiological factor in driving key diseases like cardiovascular disease and cancer. You probably won't understand risks for these diseases very well should you not control for age. But what is the counterfactual for age? If I say taking drug X doubles your risk of a stroke, that is easy -- the contrast is taking/not taking the drug. But if I say aging 15 years doubles your risk for a stroke what is the potential outcome, as age is not in any sense a fully controlled variable. 

Now, some people say age is a correlated for a whole mess of biological processes and if we measured them all then we could create this contrast, piece by piece. But that simply sidesteps the blunt fact that age is a super powerful predictor and we don't have a great sense of all of the pieces of aging. 

It seems easy because the first thing that we consider when studying (for example) mortality, is age. But what is the counterfactual -- a person being 15 years older or younger with the same life-course exposures. It is an area where the (extremely useful) tool works . . . awkwardly. And that is a good lesson -- models (even conceptual models) are useful tools but need to be carefully thought about in the context of the specific question under study. 

Monday, July 26, 2021

Feral Disinformation and Sane Vampires

Quick recap: For the story behind referring to dishonest people who pretend to believe crazy ideas, see here and here. The other term was introduced in this post and was defined as follows:

Disinformation has gone feral when:

1. It is no longer in the control of the group that created it.

2. It has continued to grow in popularity and influence.

3. It has started to evolve in such a way that the nuisance/threat it presents is as as great to the people who created it as it does to the original targets. 

We previously said that at least in the US, covid-focused anti-vaxx hysteria is currently the prime example of previously domesticated disinformation gone wild. 

The Conservative Movement spent decades depicting the scientific establishment as alarmist and corrupt because undermining it served a clear political purpose at the time. Recently this narrative took on an added usefulness as the Republicans tried to contain the fallout from the pandemic. It was an unspeakably evil position to take, greatly adding to a horrific death toll, but it had a certain ends-justify-the-means logic, "had" being the operative word.

In 2021, being the anti-vaxx party is not in the Republicans' best interest. It devastates  areas that voted for Trump and it makes the most comically crazy people imaginable the face of the GOP. On top of that, it's bad for business. 

The best messaging for the Republicans at this point would be to start referring to the "Trump vaccines" and to work the phrase "Operation Warp Speed" into every statement and interview response, regardless of topic, then take credit for the end of the pandemic. That is, however, not an option. Control of the narrative has been lost, Things have gone feral.
This has put the sane vampires of the GOP in quite the spot. Not be crazy, they know that in the medium and long term, you seldom want to be associated with the con side of a vaccination debate, but in the short term, introducing truth from the right is... challenging. 

Some have risen to that challenge.

Alabama Gov. Kay Ivey held a press conference sounding the alarm bell about the rapid spread of COVID in the state and put a significant amount of the blame on people who haven’t gotten vaccinated. “Let’s be crystal clear about this issue. And media, I want you to start reporting the facts. The new cases of COVID are because of unvaccinated folks. Almost 100% of the new hospitalizations are with unvaccinated folks. And the deaths are certainly occurring with the unvaccinated folks. These folks are choosing a horrible lifestyle of self-inflicted pain,” she said at the event yesterday in Birmingham.




Some started out boldly enough then lost their nerve.

And some have tried to lie their way out of it. (I'm from the Bible Belt, and some of my best friends, etc. etc., but take it from an old Arkansas boy, the Huckabees are soulless.)

Regardless, the sane see what's coming.




Final thought: "Does the name Custer mean anything to you?" -- Robin Williams